Cory R. Nicholas, PhD

Co-Founder and Chief Executive Officer

Dr. Cory Nicholas is a Founder and the Chief Executive Officer at Neurona Therapeutics. Cory continues to serve as the Chief Scientific Officer at the company. Before Neurona, he was a faculty member in the Department of Neurology at the University of California, San Francisco where he investigated human cortical interneuron development. Cory pioneered methods to derive interneuron precursors from human pluripotent stem cells, and he evaluated the therapeutic potential of interneuron cell therapy in multiple preclinical models of neurological disease. He maintains an adjunct faculty appointment at the University. Cory’s post-doctoral work was conducted at UCSF. His pre-doctoral research at both UCSF and Stanford University studied germline stem cells and gametogenesis. He received his Bachelor’s degree from the University of California, Berkeley.

Catherine Priest, PhD

Chief Development Officer

Dr. Catherine Priest is the Chief Development Officer at Neurona Therapeutics. Catherine was most recently the Vice President of Preclinical Development at Neurona. Prior to Neurona, she was a Senior Science Officer at the California Institute for Regenerative Medicine (CIRM), where she managed a grant portfolio of Translational and Clinical programs. Previously, Dr. Priest led the preclinical cellular therapeutics group at Geron Corporation, working on treatments for spinal cord injury, cardiovascular disease, and diabetes. During that time, the company developed the first successful IND application for an embryonic stem cell-derived cellular therapeutic that was approved by the FDA for use in a clinical trial. Dr. Priest also managed a research group at Bayer Biotechnology and was an Assistant Professor at the University of Maryland School of Medicine, where her lab focused on neuroendocrine modulation of behavior and neural circuitry. Dr. Priest received a Bachelor’s degree in Biology and Psychology from Kalamazoo College in Michigan, and a Ph.D. in Neuroanatomy and Cell Biology from the UCLA School of Medicine. She did postdoctoral training at Rockefeller University and Mt. Sinai Medical School.

Gautam Banik, PhD

Chief Technology Officer

Dr. Gautam Banik is the Chief Technology Officer at Neurona Therapeutics. Previously, Gautam was the Vice President of Manufacturing and Process Sciences at Neurona Therapeutics. Prior to joining Neurona he was Vice President of Manufacturing and Process Sciences at Cellerant Therapeutics where he developed a myeloid progenitor stem cell product derived from adult donors for the treatment of neutropenia in acute myelogenous leukemia and acute radiation syndrome. Gautam also developed an antibody drug conjugate product for the treatment of AML for early phase clinical studies. Prior to Cellerant, he worked in the Process Sciences group at Cell Genesys from 1997 to 2008. During this period, he held a number of positions with increasing responsibility including leading the development of manufacturing processes and scale up to commercial scale for cell therapy products such as GVAX immunotherapy. He also worked on a number of gene therapy and viral vector products. He conducted his post-doctoral research in Biochemical Engineering at the University of Colorado at Boulder and received his Ph.D. in Engineering Sciences from Dartmouth College. 

David Blum, MD

Chief Medical Officer

Dr. David Blum is the Chief Medical Officer at Neurona Therapeutics. David has worked in clinical development positions in the pharmaceutical industry for over 20 years, and has, as medical project leader, secured four NDA or sNDA approvals as well as approvals in EU and Canada. He previously served as senior medical director at GSK, and as Head of Neurology Clinical Research at Sunovion Pharmaceuticals. Prior to working in the pharmaceutical industry, David was in clinical practice as a neurologist at the Barrow Neurological Institute in Arizona for 10 years, where he was director of the epilepsy program. He has authored or co-authored over 50 full-length papers in neurology-related areas. He received his M.D. from the University of California at San Diego and completed neurology residency and neurophysiology fellowship at the University of California at Los Angeles.

Alessandro Bulfone, MD

Head of Operations

Dr. Alessandro Bulfone is the Head of Operations at Neurona Therapeutics where he leads all operational functions for the planning, prioritization, and execution of the company’s research and development programs. Most recently, Alessandro was head of the Biomedicine Department at CRS4 in Italy, an interdisciplinary research center focused on applying state-of-the-art computational and genomic technologies in large collaborative biomedical research projects. Previously, while leading an early-stage start-up company, he contributed to the identification and early development of putative molecular biomarkers in neuro-oncology and autoimmune diseases. In his prior career as an independent research investigator, he managed research projects at Hospital San Raffaele and Telethon Institute of Genetics and Medicine in Milan (Italy), focused on the characterization of genes involved in early forebrain development. Alessandro earned his M.D. and completed his residency in Neurology at the University of Turin, Italy. He completed his post-doctoral training in the Department of Psychiatry at the University of California, San Francisco, contributing to the early discoveries being studied further at Neurona Therapeutics.

Sheri Madrid

VP of Clinical Operations and Development

Sheri Madrid is VP of Clinical Operations and Development at Neurona Therapeutics. Prior to joining Neurona, Sheri was a clinical development consultant offering broad clinical trial support for the development of drugs, biologics and medical devices. Prior to that she served as Executive Director, Clinical Operations at Advanced Clinical, a clinical development organization that provides global services including broad clinical consulting solutions for pharmaceutical, biopharmaceutical, biotechnology, and medical device organizations. For over 26 years, she has led global clinical teams in both start up and corporate environments in multiple therapeutic areas, including interventional neuroradiology, cardiology, oncology, rare diseases and endocrinology. Sheri is recognized for her expertise in clinical trial strategy and management, process improvement and workforce planning. She is passionate about clinical research and identifying treatments that improve the lives of patients. Sheri graduated from the University of California, Irvine with a B.S. in Biology and B.A. in Social Ecology.

Sergei Shevchuk, PhD

Senior Director of Quality Assurance and Quality Control

Dr. Sergei Shevchuk is the Senior Director of Quality Assurance and Quality Control at Neurona Therapeutics. He has more than 20 years of Quality Assurance and drug development experience in the biopharmaceutical industry. Prior to joining Neurona, Sergei was a Senior Director, Quality and Compliance at Principia Biopharma, a Sanofi company, where he led Quality Management System improvement efforts and the GMP Quality team. Prior to Principia, Sergei held positions within the quality organization at Gilead Sciences, managing teams in Quality Control, as well as in clinical and commercial Quality Assurance. Sergei holds an M.S. in organic chemistry from Odessa I.I. Mechnikov National University and Ph.D. in inorganic chemistry from A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine.

James Tanaka

Director of Finance

James Tanaka is the Director of Finance at Neurona Therapeutics. Prior to joining Neurona, he worked at Cord Blood Registry, a family cord blood stem cell banking company. While at Cord Blood Registry, James held a number of positions with increasing responsibilities, building the accounting & finance team, and the accounts receivable & billing team. He also assisted with the sale of the company to a private equity firm in 2012. James received his B.S. in Business Administration from California Polytechnic State University, San Luis Obispo, and holds a CPA license.

Leo Guthart, PhD

Managing Partner, Topspin Partners

Dr. Leo A. Guthart currently manages Topspin Partners, a venture capital fund and Topspin Partners LBO, a buyout fund. The funds are both based on Long Island and invest approximately $600 million with principal focus in the venture area on biotechnology, computer security and rechargeable batteries for electric vehicles. Dr. Guthart served as a Director of Aragon Pharmaceuticals (sold to Johnson & Johnson) and Seragon Pharmaceuticals (sold to Roche-Genentech). He is presently a Director of Peloton Pharmaceuticals. Dr. Guthart was Chairman of the Board of Trustees of Hofstra University from 1993-1996, and is currently a member of the Hofstra Board of Trustees. He serves as Treasurer of Cold Spring Harbor Laboratory and is a member of its Executive Committee, an Overseer of the Hofstra-NSLIJ Medical School and a Trustee Emeritus of the Stony Brook Foundation. He was inducted into the Long Island Technology Hall of Fame. He was a Founding Director of the Long Island Research Institute and was a Trustee of the Acorn Funds, a leading growth-oriented family of mutual funds. He is a Director of AptarGroup, Inc. (NYSE), an international producer of dispensing valves, pumps and closures for pharmaceuticals and perfumes. He served as Chairman of the Security and Fire Solutions Group of Honeywell International. Until its sale to Honeywell in 2000, he served as Vice Chairman of Pittway Corporation and Chief Executive Officer of its Security Group of Companies. He also served as Chairman of Cylink Corporation for many years. Cylink was the first to offer electronic public key encryption to the commercial market. Dr. Guthart is a graduate of Harvard College where he received a B.A. degree in Physics and of Harvard Business School where he was a George F. Baker Scholar and received both an M.B.A. and a Doctorate in Business Administration with a specialty in Corporate Finance. Dr. Guthart served on the faculty of Harvard Business School and was a Ford Foundation Fellow performing research on corporate share repurchases. His articles on share repurchases have been published in the Harvard Business Review, the Financial Analysts Journal and the Journal of Finance.

Stephen Hauser, MD

Professor of Neurology, UC San Francisco, Director, UCSF Weill Institute for Neurosciences

Stephen L. Hauser, M.D. is the Robert A. Fishman Distinguished Professor and Chair of the Department of Neurology at the University of California, San Francisco. A neuroimmunologist, Dr. Hauser’s research has advanced our understanding of the genetic basis, immune mechanisms, and treatment of multiple sclerosis. Dr. Hauser is a fellow of the American Academy of Arts and Sciences and the American Academy of Physicians, and is a member of the Institute of Medicine of the National Academy of Sciences (Chair of Committee on Gulf War and Health Outcomes [2009] and Chair of Committee on Long Term Effects of Blast Exposure [2014]). He also serves the Veterans Administration as Chair of the VA Secretary’s Research Advisory Committee on Gulf War Illnesses. He is an editor of the textbook Harrison’s Principles of Internal Medicine, and has served as editor-in-chief of Annals of Neurology (2008-2014). He is a former President of the American Neurological Association and President of the Medical Staff at UCSF. He also serves on several scientific advisory boards for nonprofit organizations. Dr. Hauser has received numerous awards and honors for his work, including the Jacob Javits Neuroscience Investigator Award from the NIH, the John Dystel Prize and the Charcot Award for Multiple Sclerosis Research. In April 2010 Dr. Hauser was appointed by President Obama to the Presidential Commission for the Study of Bioethical Issues charged with advising the President on issues that may emerge from advances in biomedicine and related areas of science and technology. He is a graduate of MIT (Phi Beta Kappa) and Harvard Medical School (Magna Cum Laude). He trained in internal medicine at the New York Hospital–Cornell Medical Center, in neurology at the Massachusetts General Hospital (MGH), and in immunology at Harvard Medical School and the Institute Pasteur in Paris, France, and was a faculty member at Harvard Medical School before moving to UCSF.

Arnold Kriegstein, MD, PhD

Professor of Neurology, UC San Francisco, Co-Founder and Scientific Advisor

Dr. Arnold Kriegstein is currently the John Bowes Distinguished Professor in Stem Cell and Tissue Biology and Founding Director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at the University of California, San Francisco. Dr. Kriegstein’s research focuses on how neural stem and progenitor cells in the embryonic brain produce neurons and ways to translate this information for cell-based therapies to treat diseases of the nervous system. His lab found that radial glial cells are neuronal stem cells in the developing brain and also identified a second type of precursor cell produced by radial glial cells responsible for generating specific neuronal subtypes. He has been characterizing the progenitor cells within the developing human brain to determine the genetic profiles of specific progenitor populations, and to explore how these cells contribute to the enormous expansion of neuron number that characterizes the human cerebral cortex. Dr. Kriegstein joined the Neurology Department at UCSF in 2004 and has held academic appointments at Stanford University, Yale University, and Columbia University. He received his B.A. from Yale University and his M.D. and Ph.D. degrees from New York University in 1977 where his thesis advisor was Dr. Eric Kandel. He subsequently completed Residency training in Neurology at the Brigham and Women’s Hospital, Children’s Hospital, and Beth Israel Hospital in Boston. Dr. Kriegstein has received numerous awards including the Stanford University William M. Hume Faculty Scholar and two Javits Awards from the NIH. He was elected to the National Institute of Medicine in 2008.

Tim Kutzkey, PhD

Managing Partner, The Column Group

Dr. Tim Kutzkey serves as Chairman on Neurona’s Board of Directors. He is currently a Managing Partner at The Column Group (TCG). Since joining TCG in 2007, Dr. Kutzkey has contributed to the conception, formation, and management of many of the firm’s portfolio companies. In addition to Neurona, he is currently a Board Director of Peloton Therapeutics, a company he launched in 2010 as the President and CEO. Dr. Kutzkey also serves on the Board of Directors of Surrozen, Nura Bio, Carmot Therapuetics, Kallyope, Plexium, Synthekine and Cajal Neuroscience. Dr. Kutzkey was formerly a scientist at KAI Pharmaceuticals, focused on the discovery and development of selective protein kinase C inhibitors. Prior to KAI, he worked at UC Berkeley as a graduate student and postdoctoral scholar in the lab of Dr. Robert Tjian, completing his Ph.D. in molecular and cell biology in 2005. Dr. Kutzkey was previously educated at Stanford University.

Brad Margus

Co-Founder and Chief Executive Officer of Cerevance

Mr. Margus currently serves as Co-Founder and Chief Executive Officer of Cerevance, a private, clinical-stage drug development company focused on pursuing novel targets for brain diseases. In addition to Cerevance, Mr. Margus has co-founded several biotechnology companies including Perlegen Sciences, a tools and diagnostics company focused on using genetic variation to improve clinical decision making, and Envoy Therapeutics, focused on advancing a pipeline of compounds that acted on proteins selectively expressed in the disrupted circuitry of brain diseases. Envoy Therapeutics was acquired by Takeda Pharmaceuticals in 2012. Mr. Margus has been a member of numerous government advisory committees as well as corporate and nonprofit boards. He currently serves on the boards of Arvinas Inc., Global Genes, a non-profit organization that advocates on behalf of all rare diseases, and the non-profit A-T Children’s Project. Additionally, he serves as the Co-Chair of the Network for Excellence in Neuroscience Clinical Trials External Oversight Board at the NIH. Mr. Margus received his M.B.A. from Harvard Business School.

Cory R. Nicholas, PhD

Co-Founder and Chief Executive Officer

Dr. Cory Nicholas is a Founder and the Chief Executive Officer at Neurona Therapeutics. Cory continues to serve as the Chief Scientific Officer at the company. Before Neurona, he was a faculty member in the Department of Neurology at the University of California, San Francisco where he investigated human cortical interneuron stem cells and development. Cory pioneered methods to derive interneuron precursors from human pluripotent stem cells for transplantation into multiple animal models of neurological disease. He maintains an adjunct faculty appointment at the University. Cory’s post-doctoral work was conducted at UCSF. His pre-doctoral research at both UCSF and Stanford University studied germ cell development. He received his Bachelor’s degree from the University of California, Berkeley.

Robert Tjian, PhD

Professor of Biochemistry, Biophysics, and Structural Biology, UC Berkeley, Science Partner, The Column Group

Dr. Robert Tjian joined The Column Group as a Discovery Partner in September 2016. Prior to that he served as President of the Howard Hughes Medical Institute 2009-2016. Dr. Tjian discovered the first human proteins called transcription factors that bind to specific sections of DNA and play a critical role in regulating how genetic information is expressed into the thousands of biomolecules that keep cells, tissues, and organisms alive. His laboratory has focused on disruptions in the process of transcription that cause diseases such as cancer, metabolic syndromes, and neuro-degenerative diseases including how transcription factors control the self-renewal, pluripotency and differentiation of embryonic stem cells. He has also pioneered the use of single cell-single molecule imaging of ES cells to reveal the dynamic nature of transcription factors operating in living cells. Dr. Tjian joined the University of California, Berkeley faculty in 1979, where he assumed several leadership roles such as: Director of the Berkeley Stem Cell Center, Faculty Director of the Li Ka Shing Center for Biomedical and Health Sciences and Head of the Siebel Stem Initiative. He currently serves as scientific advisor to the Gordon and Betty Moore Foundation, The Chan Zuckerberg Initiative, and The BioHub. He is a member of the National Academy of Sciences and has received numerous awards including the Alfred P. Sloan Prize and the Louisa Gross Horwitz Prize. He served on the original SAB of Genentech and Chiron, as well as Amgen, was a co-founder of Tularik with Dave Goeddel and Steve McKnight, and was a founding Science Partner of The Column Group. He currently also serves on the Board of Directors of eLife and the Scientific Advisory Board of Eikon Therapeutics.

Erica Whittaker, PhD

VP and Head of UCB Ventures

Dr. Erica Whittaker is Vice President & Head of UCB Ventures, a €150 million strategic corporate venture fund which was set up to invest in innovative, longer term and higher risk therapeutic and digital health opportunities beyond UCB’s current focus areas. She is a Board Director for four of UCB Ventures’ portfolio companies. Erica began her career at UCB in 2010 as VP Strategy & Partnering, Research. In 2012, she became a member of an internal strategy team which shaped UCB’s Patient Value Strategy that is being implemented today. As Head of Market Access EMEA 2013-2017, Dr. Whittaker was instrumental in developing regional patient access and pricing strategies and working with affiliates to drive local execution. Prior to UCB, she spent 10 years as a top-ranked biotechnology equity analyst for Merrill Lynch in London (1999-2009). Dr. Whittaker attended Brown University (Rhode Island, USA) where she received BA degrees in Biology and in Comparative Literature. She travelled to the UK on a Marshall Scholarship and obtained a Ph.D. in Molecular Biology from the University of Edinburgh, and later an M.B.A. from Heriot-Watt University Business School in Edinburgh.

Arturo Álvarez-Buylla, PhD

Professor of Neurological Surgery, UC San Francisco

Dr. Arturo Álvarez-Buylla is a Professor in the Department of Neurological Surgery at the University of California, San Francisco, where he also serves as the Heather and Melanie Muss Endowed Chair and Principal Investigator in the Brain Tumor Research Center. Dr. Álvarez-Buylla’s research specializes in developmental neuroscience and stem cell neurobiology with special interests in neurogenesis in the adult mammalian brain, the assembly of the brain circuits, origin of brain tumors, and interneuron transplantation. His research identified the neural stem cells in the adult brain, their origin in the embryo, long-range neuronal migration in the postnatal brain and new mechanisms of neuronal translocation. His laboratory also identified the medial ganglionic eminence (MGE) as a source of young neurons that after transplantation can migrate and integrate in the postnatal and adult brain. In collaboration with other groups at UCSF, his laboratory has shown that MGE cells can induce new periods of brain plasticity, ameliorate epileptic seizures and increase pain thresholds. An ongoing interest of the Álvarez-Buylla Lab is understanding how adult neural stem cells are regulated, studying how cells derived from these progenitor cells integrate into the adult brain and which populations of MGE-derived neurons can be used therapeutically. Dr. Álvarez-Buylla joined the UCSF faculty in 2000. Prior to that he was head of lab at Rockefeller University. Dr. Álvarez-Buylla obtained his Ph.D. degree at Rockefeller University in 1988 and a Bachelor’s degree in Biomedical Research at the Universidad Nacional Autónoma de México (Mexico City, Mexico) in 1983. Dr. Álvarez-Buylla has received numerous awards including the Robert L. Sinsheimer Award in Molecular Biology, the Jacob Javits Award and the Prince of Asturias Award for Technical and Scientific Research.

Arnold Kriegstein, MD, PhD

Professor of Neurology, UC San Francisco

Dr. Arnold Kriegstein is a member of the Institute of Medicine of the National Academies, and the John Bowes Distinguished Professor in Stem Cell and Tissue Biology and Founding Director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at the University of California, San Francisco. Dr. Kriegstein’s research focuses on how neural stem and progenitor cells in the embryonic brain produce neurons and ways to translate this information for cell-based therapies to treat diseases of the nervous system. His lab found that radial glial cells are neuronal stem cells in the developing brain and also identified a second type of precursor cell produced by radial glial cells responsible for generating specific neuronal subtypes. He has been characterizing the progenitor cells within the developing human brain to determine the genetic profiles of specific progenitor populations, and to explore how these cells contribute to the enormous expansion of neuron number that characterizes the human cerebral cortex. Dr. Kriegstein joined the Neurology Department at UCSF in 2004 and has held academic appointments at Stanford University, Yale University, and Columbia University. He received his B.A. from Yale University and his M.D. and Ph.D. degrees from New York University in 1977 where his thesis advisor was Dr. Eric Kandel. He subsequently completed Residency training in Neurology at the Brigham and Women’s Hospital, Children’s Hospital, and Beth Israel Hospital in Boston. Dr. Kriegstein has received numerous awards including the Stanford University William M. Hume Faculty Scholar and two Javits Awards from the NIH. He was elected to the National Institute of Medicine in 2008.

John Rubenstein, MD, PhD

Professor of Psychiatry, UC San Francisco

Dr. John Rubenstein is a Professor in the Department of Psychiatry at the University of California, San Francisco. He also serves as a Nina Ireland Distinguished Professor in Child Psychiatry at the Nina Ireland Laboratory of Developmental Neurobiology. His research focuses on the regulatory genes that orchestrate development of the forebrain. In the mammalian embryo, the forebrain is the portion of the neural tube where primitive cells are organized to form the cerebral cortex, the basal ganglia and other components of the adult brain — the structures of the human brain most involved in key functions such as speech, language, cognition and fine motor skills. Dr. Rubenstein’s lab has demonstrated the role of specific genes in regulating neuronal specification, differentiation, migration and axon growth during embryonic development and on into adulthood. His work aims to elucidate mechanisms underlying human neurodevelopmental disorders such as autism, schizophrenia, epilepsy and mental deficiency. Dr. Rubenstein joined the Psychiatry Department at UCSF in 1991. He received his Ph.D. and M.D. degrees in 1982 and 1986 and completed his medical residency at Stanford University. He obtained his B.S. in Chemistry from Stanford University in 1977. Dr. Rubenstein was elected to the National Institute of Medicine in 2006.